BioPharmaPro™ Sealing Solutions

Seals perform critical functions in chromatography equipment. By eliminating dead space, they protect the product from contamination and prevent leakage to the outside environment. They must withstand harsh environments and be suitable for use with biopharmaceuticals. Our broad range of high-performance sealing solutions, from the versatile O-Ring to complex multi-faceted geometries, includes seals for static and dynamic applications in a wide range of materials, including PTFE, engineered plastics and elastomer compounds.

BioPharmaPro™ Advanced Composites

Advanced composite materials are ideal for chromatography columns, since they are uniquely lightweight, inert and robust. Our BioPharmaPro™ advanced composite columns are designed to replace stainless steel or acrylic, multi-use columns and can be manufactured in unlimited dimensions to meet a full range of size requirements. Produced with polypropylene thermoplastic materials, the columns can be recycled, offering a more sustainable single-use solution.

Integrated Solutions

The columns can be combined with other BioPharmaPro™ capabilities to provide a complete, pre-packed system, into which only the chromatography media needs to be added.

BioPharmaPro™ Thermoplastic Molded Components

Connectors and flow distributors with fluid-flow geometries are produced utilizing our advanced molding capabilities. Thermoplastic molded components are available in high-temperature, engineering-grade resins, polysulfone (PS), polycarbonate (PC) and polyether ether ketone (PEEK). Components can be enhanced with soft touch overmolding, high-volume insert overmolding through automation, and value-added services, including laser scribing and pad printing.

BioPharmaPro™ Braided, Reinforced Hose

BioPharmaPro™ braided, reinforced silicone hoses are designed for demanding medical applications. In chromatography equipment, they facilitate the separation of media. They are designed for high-pressure applications and withstand extreme temperatures while maintaining flexibility at temperatures from -80 °F to 500 °F/-62 °C to +260 °C. They can undergo repeated sterilization-in-place (SIP) and cleaning-in-place (CIP) cycles. Our braided, reinforced hoses are manufactured with the same platinum-cured silicone as used for our BioPharmaPro™ silicone tubing.

Liquid Chromatography

Liquid chromatography is a separation technology used in biopharmaceutical downstream processing. The media is crucial in chromatography technology since it separates specific substances from the mixture.  

After the biopharmaceutical production process, the mixture enters the chromatography system and pressure guides it through the separation media, which isolates and purifies the target substance. Different chromatography techniques, such as positive and negative ions, different pH values, particle sizes or adsorption can be employed.