Combination products offer several advantages when compared with drug delivery via oral, injection, and infusion methods:

• Controlled release of the Active Pharmaceutical Ingredients (API): the controlled release as opposed to the bolus-type delivery facilitates consistent API concentrations within an optimal therapeutic range
• Targeted delivery of the API: this strength of drug-eluting devices, particularly implanted devices, permits higher therapeutic dosages to be delivered while minimizing adverse side effects
• Improved Patient Compliance: combination products improve patient compliance and most healthcare practitioners agree that within an aging population, compliance becomes less certain and therefore more important
• Prevention of infection: an API added to a device can improve the device function and help to prevent local, as well as systemic infection

Drug-eluting medical devices can be used to treat a wide range of medical conditions. Some application examples include:

• Female Healthcare
• Wound Care
• Steroidal Collars
• Pacemaker Leads
• Ophthalmic Devices
• Antimicrobials