Advantages of combination products
Combination products offer several advantages when compared with drug delivery via oral, injection, and infusion methods:
- Controlled release of the Active Pharmaceutical Ingredients (API): the controlled release as opposed to the bolus-type delivery facilitates consistent API concentrations within an optimal therapeutic range
- Targeted delivery of the API: this strength of drug-eluting devices, particularly implanted devices, permits higher therapeutic dosages to be delivered while minimizing adverse side effects
- Improved Patient Compliance: combination products improve patient compliance and most healthcare practitioners agree that within an aging population, compliance becomes less certain and therefore more important
- Prevention of infection: an API added to a device can improve the device function and help to prevent local, as well as systemic infection
Drug-eluting medical devices can be used to treat a wide range of medical conditions. Some application examples include:
- Female Healthcare
- Wound Care
- Steroidal Collars
- Pacemaker Leads
- Ophthalmic Devices
- Antimicrobials
Our Drug Device Services
Literature
Combination Products
Start-to finish drug eluting product development and manufacturing in an FDA compliant facility
Fighting Hospital Acquired Infection
Exploring methods of combining silicone tubing with APIs
Supporting the Advancement of Drug-Eluting Devices
Presenting alternative methods for addition of API to silicone components for drug-eluting medical devices